CIALYN - DRIADA MEDICAL


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What is Cialyn (Tadalafil)?
Cialyn has a scientific name — tadalafil. It’s an effective medication that helps cope with erectile problems. It is primarily used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). The medication belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Cialyn was approved by the FDA in 2003; since that time, it has become one of the most prescribed medications for ED.

ERECTILE DYSFUNCTION STATISTICS
Erectile dysfunction is a common condition that affects a significant proportion of men worldwide. As recent statistics show, erectile dysfunction affects approximately 52% of men aged 40–70 years. This problem makes Cialyn a critical therapeutic. This tendency increases with age, affecting about 40% of men by age 40 and nearly 70% of men by age 70. This condition not only impacts the quality of life but also contributes to psychological stress, anxiety, and depression among affected patients.

BPH Statistics
In addition to ED, Cialyn is used to treat the symptoms of benign prostatic hyperplasia (BPH). The condition affects the prostate gland in men. Older men usually suffer from it, which is approved by studies. They show that about 50% of men aged 51–60 years and up to 90% of men older than 80 years experience symptoms of BPH. Symptoms include difficulty in urination, frequent urination, and urinary retention, which significantly impact the quality of life.

Usage and Popularity
Cialyn is available in various forms. Patients can take it daily or upon necessity. Thus, pills come as a versatile option for men with different lifestyles and needs. The daily version allows for spontaneous sexual activity without the need to plan ahead. Still, the as-needed version provides flexibility for those men who prefer to take medication only when required. Such flexibility acts in favor of the popularity and widespread use of Cialyn.

MECHANISM OF ACTION
PDE5 Inhibition
Cialyn regulates the inhibition of the enzyme phosphodiesterase type 5 (PDE5). The element is present in tissues, and the soft tissues of the penis are no exception. Phosphodiesterase type 5 is responsible for the breakdown of cyclic guanosine monophosphate (cGMP) in any organ. The component is an important ingredient of the drug, as it improves blood flow in the penis.

cGMP and Smooth Muscle Relaxation
The corpus cavernosum of the male penis releases nitric oxide (NO) when actively stimulated. The Cialyn component enhances the activity of the enzyme guanylate cyclase, which in turn increases the content of cGMP. This process leads to the relaxation of the soft muscle tissue of the penis, as the enzyme penetrates its cells. With powerful and strong blood flow, an erection occurs instantly. The medication counteracts the formation of the PDE5 component at the cellular level. As a result, the content of the cGMP component increases, and penis hardening due to intense blood flow naturally improves. This is the restoration of the organ’s sensitivity to erotic stimulation.

Extended Half-Life
One of the strongest advantages of Cialyn is that it’s not removed from the body very quickly. The duration of the half-life is almost a day — approximately 17.5 hours. This fact means that the activity of the active substances lasts much longer compared to PDE-5 inhibitors such as vardenafil (Levitra) and sildenafil (Viagra). As a result, the activity of the active substance lasts up to 36 hours. In this regard, the medicine is called the “weekend pill”. When taking Cialyn, a man does not have to worry about the exact timing for a successful erection. Sexual activity is guaranteed throughout the weekend.

Selectivity for PDE5
Cialyn is a drug with high selectivity in the treatment of PDE5. At the same time, active ingredients work very effectively and are absolutely safe for men’s health. The selectivity indicator significantly reduces the likelihood of side effects and unexpected reactions from taking the medication. Since PDE5 is found in the soft tissues of the prostate gland and penis, the tablet is quite effective in eliminating problems with prostate adenoma and ED.

DETAILED USES
Primary Use: Improving Erectile Function
The main purpose of pills is to treat erectile dysfunction. According to studies, Cialyn improves hardening and swelling of the penis in men suffering from lack of sexual arousal. Tadalafil supports a natural erection with increased blood flow after active stimulation of the erogenous zone in a natural way. Many years of clinical trials and practical research confirm and document the beneficial effects of the drug.

Clinical studies confirm the effectiveness of Cialyn in improving erectile function in men with various degrees of severity of erectile dysfunction. As the active component of the tablets, tadalafil acts specifically to accelerate blood flow through the vessels of the penis in all patients, regardless of their demographics and the difficulty of getting an erection. One of the studies examined the effects and safety of tadalafil. Research was carried out to eliminate mild and severe problems of the erectile organ. During the observation process, a group of scientists noted that serious hardening and swelling of the penis occurs under the condition of therapeutic use of tadalafil. As the drug was taken, it was found that the component works well in different age categories of patients and is guaranteed to strengthen erections regardless of the severity of the disease.

The second direction of clinical trials was carried out to check the duration of action of the drug, as well as the safety and reliability of the targeted effect on the patient’s painful areas. As a result, it was concluded that tadalafil can be used in safe proportions for six months. Positive results were noted in 80% of male subjects. The drug testing period allowed us to draw other important conclusions about the easy and safe tolerability of the ingredient. The expert group concluded that the drug can be taken in the presence of concomitant diseases. For example, the action of tadalafil is not affected by high blood pressure, diabetes, or diseases of the cardiovascular system. It turns out that the reliability of using the drug for men suffering from these diseases is equally high and does not depend on the course of chronic diseases. Cialyn shows a positive result in its targeted effect on solving the patient’s problem.

Reducing Blood Pressure
Cialyn is designed to eliminate problems with blood flow into the vessels of the male genital organ. Patients note that the remedy works well in the fight against hypertension. As a result, instead of one problem, the drug has a beneficial effect in two directions and is indicated for men with high blood pressure and erectile dysfunction. Tadalafil stands as the main active ingredient of the treatment. By its chemical structure, it’s a phosphodiesterase type 5 (PDE5) inhibitor. The component gently acts on the elasticity of blood vessels, which expands and increases the level of cyclic guanosine monophosphate (cGMP) in smooth muscle cells. The elasticity of the vascular walls indicates relaxation of the tone. As a result of the dilation of blood vessels, blood flow increases significantly, and the path remains clear, so the pressure does not increase. Long-term laboratory studies demonstrate a decrease in diastolic and systolic blood pressure. Over a long period of time, even with the gradual removal of Tadalafil from the body, the elasticity of the vascular walls continues to remain high. In this regard, Cialyn fights problems with hardening the blood vessels of the penis, and at the same time improves the well-being of hypertensive patients.

Improving Tissue Tropism and Prostate Health
Statistical examination of patients who received Tadalafil showed that the medication promotes free blood flow and tissue tropism. This fact indicates that men receive additional prospects for improving their prostate health. Patients receive basic medications for benign prostatic hyperplasia (BPH). Active ingredients significantly reduce symptoms due to the gradual relaxation of the muscle tissue of the bladder and prostate gland. As a result, urine flows out like in healthy people. It is a known fact that with prostate adenoma, the prostate gland becomes significantly enlarged and partially blocks the urination channel. Patients often feel the urge to urinate, urinary retention, and weak outflow. Cialyn causes a concomitant action, which helps relax the bladder neck and prostate muscle cells. As a result, treatment of problems with penile erection leads to an improvement in the condition of prostate adenoma. Thus, the supplement comes as a unique dual-action drug for men who have prostate adenoma and poor urine flow.

Workout Enhancement for Bodybuilders
Men who train to build muscles take Cialyn to open up the blood vessels in the muscles of the arms, legs, and throughout the body by increasing elasticity and improving blood flow. This circumstance makes training much easier. PDE inhibition may help improve muscle growth by allowing greater blood flow to the soft tissue. According to research results, Tadalafil medications significantly increase endothelial function and muscle mass. Thanks to this action, the effectiveness of training increases significantly, which makes the drug beneficial for bodybuilders.

PDE inhibitors significantly reduce inflammation after gym training and physical exercise. Medication components contribute to the consistent and gradual restoration of health and maintain the athletic shape of any bodybuilder.

Post-Cycle Therapy in Steroid Users
Cialyn has been observed to increase testosterone levels, which can be used during post-cycle therapy (PCT). Studies have indicated that PDE5 inhibitors can have a positive effect on serum testosterone levels, making Cialyn a useful supplement in PCT.

Improving Fertility
Erectile dysfunction can negatively impact fertility by reducing the frequency and quality of sexual intercourse. Thus, by taking Cialyn, men manage to improve erectile function, which enhances fertility indirectly. Moreover, Cialyn consumption improves the quality of sperm cells and seminal fluid. In particular, it affects motility, the percentage of nemasperms, and the volume of seminal fluid.

DOSAGES, SIDE EFFECTS, AND PRECAUTIONS
Dosages
Cialyn is available in various dosages, ranging from 2.5 mg to 20 mg. For patients who suffer from erectile dysfunction, the recommended dose starts from 10 mg. They should take it right before an expected sexual activity. However, note that the dosage can be adjusted, depending on efficacy and tolerability. If men prefer to take the treatment daily, a lower dose of 2.5 mg or 5 mg is recommended.

Dosage Adjustments
Depending on patients’ individual response and tolerance, some men require Cialyn dosage adjustment. Some men need a lower dose of 5 mg to achieve the desired effect, while others may require a maximum dose of 20 mg. Thus, dosages are adjustable and depend on the severity of the condition and individual characteristics of the body.

Side Effects
The treatment is generally beneficial, but some side effects are still reported. Thus, Cialyn may cause the following drawbacks:

About 15% of patients have mild headaches.
Approximately 10% of consumers have flushing effects, which causes a temporary redness of the face and neck.
About 5% of users experience back pain. Typically, pain is mild to moderate in severity.
Nasal congestion is observed in about 5% of cases and is usually resolved without treatment.
More serious side effects, although rare, include:

Vision changes, such as blurred vision or a blue tinge to vision.
Hearing loss. It may be a sudden decrease or loss of hearing.
Priapism. It’s a condition when an erection lasts longer than four hours. It can cause permanent damage if not treated promptly.
PRECAUTIONS
Individuals who have problems with the cardiovascular system should take the medication with caution, as it can interact with nitrates and cause a significant drop in blood pressure. When consulting a physician about consuming Cialyn, it’s important to disclose all medications and supplements to avoid potential drug interactions. Patients with severe liver or kidney damage should use Cialyn under strict medical supervision.

DRUG INTERACTIONS
Cialyn can interact with several medications, including:

Nitrates. They are often used for chest pain (angina), which can lead to a dangerous drop in blood pressure.
Alpha-blockers. Such medications are used to treat high blood pressure and BPH, which can also cause a significant drop in blood pressure.
Antihypertensives. Drugs are used to treat high blood pressure, requiring careful monitoring to avoid hypotension.
SPECIAL POPULATIONS
The following categories of people should take Cialyn with caution:

Elderly patients. Aged men’s bodies are more sensitive to the effects of Cialyn, which is why they may require dose adjustments.
Patients with hepatic impairment. Constant monitoring of their body’ conditions is required due to altered drug metabolism.
Patients with renal impairment. They may require dose adjustments, depending on kidney function.
HOW TO STORE?
Keep away from children.
Keep in a cool, dry place, away from direct sunlight.
Store at room temperature.
Do not use it after the expiry date.
FAQ
How many hours does Tadalafil last?
The average duration of the product’s effect is 17.5 hours.

When is the best time to take Tadalafil?
The answer depends on the treatment method. If you consume the drug on a daily basis, then you should take pills regularly at the same time of the day. If you prefer at-need consumption, it’s better to take pills at least half an hour (or better an hour) before an expected sexual activity to guarantee sufficient strength of the penis.