CLOMILAD - DRIADA MEDICAL


100 tabs x 25 mg/tab


DESCRIPTION
Clomiphene citrate is an antiestrogen belonging to the triphenylethylene group. It is classified as selective estrogen receptor modulator with mixed agonist and antagonistic properties This means that in certain tissues they block the action of estrogen by binding to receptors, while there is an exception – the bone tissue, where, on the contrary, it. activates estrogen receptors, and its useful feature to prevent osteoporosis.

MECHANISM OF ACTION
In men, both drugs act as antiestrogens in their ability to interfere with the negative feedback of estrogens to the hypothalamus and stimulate increased production of GnRH (gonadoliberin), which increase the production of LH and FSH hormones by the pituitary gland, triggering the synthesis of testosterone and sperm in the testicles.

Clomiphene acts on estrogen receptors in the pituitary gland and ovaries. By binding the estrogen receptors in the pituitary gland, clomiphene breaks the negative feedback mechanism, i.e. if usually estrogens, acting on the pituitary gland, reduce the production of FSH and LH, then when taking clomiphene this does not happen. Clomiphene does not directly affect the level of estrogen in the blood.Thus, clomiphene acts as an antagonist of estrogens and eliminates their inhibitory effect on the hypothalamus and pituitary gland, contributing to a more rapid restoration of their function.

HOW TO USE
Recovery after the cycle: Depending on the severity, up to 150 mg is used in the first days and then gradually reduced to a dosage of 50-25 mg within two weeks, then they are guided by the lab tests. After light courses such as for example oxandrolone solo, it is enough to drink 50 mg for the first week and then 25 mg for the second week. In any case, the recommendations are only approximate, each case is individual and should be considered separately.

Therapy to increase testosterone levels: 50 to 25 mg per day, and adjust the dosage according to the tests. The vast majority of men over 35 are satisfied with a dosage of 25 mg per day, they note an increase in testosterone, libido and energy levels, and also do not experience any side effects.

EFFECTS
Blocking estrogen receptor (mostly active in brain)
Increase production of endogenous testosterone(as the part of PCT or anti-age therapy)
Strengthens bones
Prevents the estrogen induced gynecomastia
SIDE EFFECTS
Breast tenderness or discomfort
Headache
Nausea
Diarrhea
Flushing
Blurred vision or other visual disturbances
Note that Clomiphene side effects are very rare
PROFILE
Half-life: 5-6 days
Frequency of intake: 1 time day
CONTRAINDICATIONS
Hypersensitivity to clomiphene citrate or components of the formulation
Pregnancy
Breastfeeding
History of hepatic impairment
Hepatic disease
Abnormal uterine bleeding
Uncontrolled adrenal dysfunction
Non-PCOS related ovarian cyst
Organic intracranial lesions
Uncontrolled thyroid disease
Pituitary tumor
HOW TO STORE
Keep away from children
Keep in a cool, dry place, away from direct sunlight
Store at room temperature
Do not use after the expiry date