Triiodothyronine, commonly known as T3, is a thyroid hormone that plays a crucial role in various physiological processes, influencing growth, development, metabolism, body temperature, and heart rate.



Benefits:

Regulates essential physiological functions, including metabolism, body temperature, and heart rate.
T3 is involved in the metabolism of carbohydrates, fats, and proteins, ensuring proper cellular functions.
Supplementation with T3 is beneficial for individuals suffering from hypothyroidism, restoring metabolism and addressing issues such as body fat gain, difficulty in fat loss, loss of energy, and potential hair loss.
Low doses of T3 are generally used for treating hypothyroidism, aiming to restore the proper functioning of metabolism.
Athletes may use T3 to enhance direct fat loss, especially when combined with a calorie-restricted diet. However, this practice is not recommended without the concurrent use of anabolic steroids.
Higher doses required for enhanced fat loss can lead to lean tissue loss and depletion of ATP, necessitating the use of an anabolic protectant.


Side Effects:

Increases the basal metabolic rate, resulting in elevated oxygen and energy consumption by the body.
Stimulates the production of RNA Polymerase I and II, enhancing protein synthesis. However, excessive T3 levels may lead to an imbalance between protein synthesis and degradation.
Potentiates the effects of β-adrenergic receptors on glucose metabolism, increasing the breakdown of glycogen and synthesis of glucose.
Stimulates the breakdown of cholesterol and increases the number of LDL receptors, promoting lipolysis.
Increases heart rate and force of contraction, leading to elevated cardiac output and changes in blood pressure, commonly observed in hyperthyroidism.


Precautions and Dosage Instructions:

Prior to T3 use, it is strongly recommended to undergo blood work to assess TSH, T4, and T3 serum levels.
Cycles of T3 should not exceed 6 weeks, and discontinuation should not be abrupt. Dosage adjustments should follow a gradual reduction, typically 15-25 mg every 3-4 days, mirroring the gradual buildup.