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Hexarelin, also known as Examorelin and Hexarelin Acetate, is a potent, synthetic hexapeptide and a highly selective agonist (initiates a physiological response when combined with a receptor) of the ghrelin/growth hormone secretagogue receptor and a growth hormone secretagogue.

Usage

Hexarelin is used to stimulate natural growth hormone production, promoting lean muscle growth, rapid fat loss, increased tendon and ligament strength, enhanced flexibility, and better recovery from injuries and training sessions.

By increasing natural growth hormone levels, Hexarelin also enhances production of Insulin-like Growth Factor 1 (IGF-1) in the body. This further drives the growth of lean muscle tissue, improving strength and body composition. Likewise, Hexarelin promotes significant gains in athletic performance, preventing musculoskeletal injury while reducing recovery time between training sessions. In addition, its method of action prevents many of the negative side effects of synthetic hGH administration, including the shutdown of natural growth hormone production

Mechanism of Action

Growth hormone is made and released by the pituitary gland. Hexarelin functions to enhance the natural growth hormone production by amplifying the natural growth hormone releasing signal. This results in a greater secretion of growth hormone from the pituitary gland. Hexarelin then suppresses a hormone in the body called somatostatin, also known as growth hormone inhibiting hormone. Somatostatin causes the body to reduce its natural growth hormone output. By limiting the action of somatostatin, growth hormone production is escalated, resulting in significantly increased natural growth hormone levels.

Hexarelin can bind to and activate the growth hormone secretagogue receptor in the brain similar to its natural counterpart ghrelin. Hexarelin has been studied to be much more potent and stable than gherlin.

The outlying distribution of growth hormone secretagogue in the heart and blood vessels suggests that Hexarelin may have direct cardiovascular actions beyond growth hormone release and neuroendocrine effects.

Administration

Mode of Administration: Subcutaneous injection to a fleshy part of the body, typically to the stomach or abdominal area. Hexarelin can also be taken orally.

Before administering Hexarelin, always be sure to use a clean and sterile syringe.

Hold the Hexarelin vial upright and insert the syringe in the center of the cap.
Draw the plunger until you have the correct amount (see ‘Dosage’ below) in the syringe and carefully remove it.
Before administering the syringe, use alcohol to cleanse the area of skin.
Pinch the skin around the area to be injected, leave about 2 cm on each side.
Hold the syringe at a 90 degree angle to your skin and swiftly insert the syringe.
Depress the plunger fully, until the syringe is empty, and carefully draw out.

Dosage

Dosage Amount: 200mcg - 300mcg daily, administering 100mcg at a time

Hexarelin is generally administered 2-3 times daily at dosages of 100mcg per administration. As Hexarelin is best suited for athletic performance enhancement rather than anti-aging purposes, it is commonly administered at least 2 times per day to increase growth hormone as much as possible in the limited duration of a cycle (up to 16 weeks). These dosages provide a substantial increase in growth hormone output to facilitate muscle growth, strength gain, fat loss, and recovery from training and injury. For best results, it is recommended to avoid eating one hour before and after administering Hexarelin.

Side Effects

Common side effects of Hexarelin can include feelings of tiredness or lethargy, as growth hormone can increase the desire for sleep as well as its quality and restorative capabilities. Although Hexarelin is a growth hormone releasing peptide, it does not stimulate an increase in appetite through increased ghrelin activity.

Excess dosages may lead to water retention as well as tingling or numbness in the hands and feet. This can be a sign that the dosage is too high and should be reduced. Hexarelin may have a stimulatory effect on adrenocorticotropic hormone (ACTH), cortisol, and prolactin. Though not an issue for the vast majority of users, this may cause interactions with certain medications or unwanted effects in individuals with certain health conditions.

Benefits

Increase growth of lean muscle
Acceleration of weight loss/ fat loss
Increase of tendon and ligament strength
Enhancement of flexibility and joint health
Promotion of quicker recovery from injuries and training
Resistance to musculoskeletal injury
Improvement of sleep quality
Enhancement of athletic performance and physical capacity